A decline in glycolytic ATP production is the fundamental mechanism limiting lifespan; species with an optimal rate of decline over time survived

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OpenAI would retain control over how technical safeguards are implemented and which models are deployed and where, and would limit deployment to cloud environments rather than “edge systems.” (In a military context, edge systems are a category that could include aircraft and drones.) In what would be a major concession, Altman told employees that the government said it is willing to include OpenAI’s named “red lines” in the contract, such as not using AI to power autonomous weapons, conduct domestic mass surveillance, or engage in critical decision-making.

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Patient leaflets on weight-loss injections state that gallstones are a "common" side effect, and in medical trials the injections also sometimes led to inflammation of the gallbladder. For example in Mounjaro, it has been reported this may affect up to 1 in 100 people.